phorbol — The parent alcohol of the cocarcinogens, which are 12,13(9,9a) diesters of p. found in croton oil; the hydrocarbon skeleton is a cyclopropabenzazulene; p. esters mimic 1,2 diacylglycerol as activators of protein kinase C. * * * phor·bol fȯr… … Medical dictionary
Phorbol — Chembox new Name = Phorbol ImageFile = Phorbol.png ImageName = Phorbol IUPACName = 1,1a,1b,4,4a,7a,7b,8,9,9a decahydro 4a,7b,9,9a tetrahydroxy 3 (hydroxymethyl) 1,1,6,8 tetramethyl 5H cyclopropa [3,4] benz [1,2 e] azulen 5 one Section1 = Chembox… … Wikipedia
phorbol ester — any of several esters of phorbol that are potent cocarcinogens; they are structurally similar to diacylglycerol and can activate protein kinase C. They are used frequently in research to enhance the induction of mutagenesis or tumors by… … Medical dictionary
phorbol — ˈfȯrˌbȯl, ˌbōl noun ( s) Etymology: International Scientific Vocabulary phorb (from Greek phorbē pasture, fodder) + ol (I); originally formed in German more at pheophorbide : an alcohol C20H28O … Useful english dictionary
C1 domain — Pfam box Symbol = C1 1 Name = Phorbol esters/diacylglycerol binding domain (C1 domain) width =200 caption = C1 domain of PKC delta (1ptr) Middle plane of the lipid bilayer black dots. Boundary of the hydrocarbon core region blue dots (cytoplasmic … Wikipedia
RASGRP3 — RAS guanyl releasing protein 3 (calcium and DAG regulated), also known as RASGRP3, is a human gene.cite web | title = Entrez Gene: RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG regulated)| url =… … Wikipedia
Chimerin 2 — Chimerin (chimaerin) 2 PDB rendering based on 1xa6 … Wikipedia
Croton tiglium — Purging Croton Croton tiglium Scientific classification Kingdom: Plantae … Wikipedia
PKC alpha — Protein kinase C, alpha, also known as PRKCA, is a human gene. PBB Summary section title = summary text = Protein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second… … Wikipedia
PRKCD — Protein kinase C, delta, also known as PRKCD, is a human gene. PBB Summary section title = summary text = Protein kinase C (PKC) is a family of serine and threonine specific protein kinases that can be activated by calcium and the second… … Wikipedia